View abstract. Shiroky JB, Neville C, Esdaile JM, et al. Paediatr.Perinat.Epidemiol. View abstract. 2015;122(4):478-90. 2013 23;381(9871):1029-36. Arthritis Rheum 1996;39:723-31. Get it Saturday, Jan 9. Ophthalmic Physiol Opt. Treatment of hyperhomocysteinemia in renal transplant recipients. Mooijaart, S. P., Gussekloo, J., Frolich, M., Jolles, J., Stott, D. J., Westendorp, R. G., and de Craen, A. J. Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus study. Lancet 2-3-1990;335(8684):293. Does folic acid decrease plasma homocysteine and improve endothelial function in patients with predialysis renal failure? Megaloblastic anemia due to sulphasalazine responding to drug withdrawal alone. Am.J Clin.Nutr 1975;28(5):465-470. Am J Hypertens. View abstract. Effects of folic acid and zinc sulfate on male factor subfertility: a double-blind, randomized, placebo-controlled trial. Cochrane Database Syst Rev. 4.5 out of 5 stars 172. B., and Majumdar, A. P. Folic acid supplementation inhibits recurrence of colorectal adenomas: a randomized chemoprevention trial. Clin J Am Soc Nephrol. Folic acid and vitamin B-12 supplementation and common infections in 6-30-mo-old children in India: a randomized placebo-controlled trial. Drugs 1985;30:145-55. Fulda, Germany, 20-22 November 1996. Kaisar, M., Isbel, N., and Johnson, D. W. Cardiovascular disease in patients with chronic kidney disease. A clinical case of severe megaloblastic anemia during treatment with primidone. J Rheumatol 1998;25:441-6. Kulier, R., de, Onis M., Gulmezoglu, A. M., and Villar, J. Nutritional interventions for the prevention of maternal morbidity. View abstract. Crit Rev.Food Sci.Nutr. Curr Opin.Clin Nutr Metab Care 2007;10(1):32-39. View abstract. Decline in memory and thinking skills in older people that is more than what is normal for their age. 2017;16(9):750-760. Gaziano JM, Glynn RJ, Christen WG, et al. View abstract. View abstract. Pharmacist's Letter / Prescriber's Letter 1999:15(12);151206. Am J Clin Nutr 2000;72:324-32. Taking a specific nutritional supplement with added folic acid and possibly vitamin B12 does not seem to prevent infections in the lungs in children at risk of malnutrition. J.Am.Soc.Nephrol. View abstract. Free from artificial colors, artificial flavors, sugar, yeast, starch, and wheat, Non-GMO, free from gluten, wheat, yeast, soy, sugar, and dairy, Produced in GMP-certified facilities in the USA and Canada, Free from wheat, dairy, soy, yeast, sugar, Free from artificial flavors, colors, and preservatives, Free from gelatin, preservatives, and artificial colors and flavors, Free from gluten, dairy, lactose, starch, and sugar, No preservatives, artificial flavors, or colors, Some customers have reported mild skin reactions. View abstract. Southeast Asian J Trop Med Public Health 1983;14(3):317-323. 2020. View abstract. Int J Cancer 2001;91(2):260-263. Am J Med Genet. Folic Acid 5mg - Bulk Pack for 480 Days - only 1/4 Tablet a Day - Vegan - high dose folic Acid - 120 Tablets. J Cancer Res Clin Oncol 1993;119:549-54. Adverse neuropsychiatric effects of anticonvulsant drugs. View abstract. J Am Acad Dermatol 1993;28:466-9. Effect of antacid and H2 receptor antagonists on the intestinal absorption of folic acid. View abstract. Hagerman, R. J., Murphy, M. A., and Wittenberger, M. D. A controlled trial of stimulant medication in children with the fragile X syndrome. Clarke, R., Lewington, S., Sherliker, P., and Armitage, J. Long-term diuretic therapy in hypertensive patients: effects on serum homocysteine, vitamin B6, vitamin B12, and red blood cell folate concentrations. When taking folic acid supplements, it is important to know how to manage the timing of the supplement. Source Naturals was one of the leading companies in making formulations that contain multiple herbs and vitamins. View abstract. View abstract. Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial. Cancer Epidemiol.Biomarkers Prev. J Am Coll Cardiol 2018;71(22):2570-84. View abstract. View abstract. Am J Clin Nutr 2005;82(1):26-31. View abstract. All rights reserved. Stites, T. E., Bailey, L. B., Scott, K. C., Toth, J. P., Fisher, W. P., and Gregory, J. F., III. View abstract. View abstract. Nutrients. Paediatr.Perinat.Epidemiol. Cochrane.Database.Syst.Rev 2001;(3):CD001056. A double-blind, randomized, placebo-controlled, parallel study. 2019 Sep;98(37):e17095. Belizan, J. M., Villar, J., Bergel, E., del, Pino A., Di, Fulvio S., Galliano, S. V., and Kattan, C. Long-term effect of calcium supplementation during pregnancy on the blood pressure of offspring: follow up of a randomised controlled trial. Acute megaloblastic anemia induced by high-dose trimethoprim-sulfamethoxazole. J Hypertens. Arya, R., Gulati, S., Kabra, M., Sahu, J. K., and Kalra, V. Folic acid supplementation prevents phenytoin-induced gingival overgrowth in children. Sundown Naturals Folic Acid is a vegetarian-friendly folic acid supplement. View abstract. Dement.Geriatr Cogn Disord. J.Natl.Cancer Inst. Gum enlargement caused by the drug phenytoin. What's more, folate can be lost from foods during storage or destroyed by cooking. Shirodaria, C., Antoniades, C., Lee, J., Jackson, C. E., Robson, M. D., Francis, J. M., Moat, S. J., Ratnatunga, C., Pillai, R., Refsum, H., Neubauer, S., and Channon, K. M. Global improvement of vascular function and redox state with low-dose folic acid: implications for folate therapy in patients with coronary artery disease. Ma J, Stampfer MJ, Giovannucci E, et al. View abstract. Am.J Clin.Nutr 2005;82(4):717-718. Hogeveen, M., den, Heijer M., Schonbeck, Y., Ijland, M., van, Oppenraaij D., Gunnewiek, J. K., and Blom, H. J. View abstract. View abstract. Landgren F, Israelsson B, Lindgren A, et al. Int J Clin Pract. Prasad AS, Lei KY, Moghissi KS, et al. Mayer O, Simon J, Rosolova H, et al. Cochrane Database Syst Rev. Schizophrenia. View abstract. Efficacy of folic acid therapy on the progression of chronic kidney disease: The renal substudy of the China stroke primary prevention trial. Lopez-Camelo, J. S., Orioli, I. M., da Graca, Dutra M., Nazer-Herrera, J., Rivera, N., Ojeda, M. E., Canessa, A., Wettig, E., Fontannaz, A. M., Mellado, C., and Castilla, E. E. Reduction of birth prevalence rates of neural tube defects after folic acid fortification in Chile. View abstract. The effect of folic acid and iron in the prevention of nutritional anaemias in pregnancy in Nigeria. Early research suggests that folate might reduce the risk of gout. Lin, J., Lee, I. M., Song, Y., Cook, N. R., Selhub, J., Manson, J. E., Buring, J. E., and Zhang, S. M. Plasma homocysteine and cysteine and risk of breast cancer in women. This is why we are discussing when to take folic acid. View abstract. ⓘ If you buy something after visiting a link below, we get a commission. 1988;6(3):469-475. One tablet daily of this effective product is enough to get the many folic acid benefits that we mentioned before. View abstract. 2009;20(5):779-788. View abstract. View abstract. Burland, W. L., Simpson, K., and Lord, J. View abstract. 1-3-2007;99(1):64-76. Cochrane Database Syst Rev. Clarke, R., Halsey, J., Bennett, D., and Lewington, S. Homocysteine and vascular disease: review of published results of the homocysteine-lowering trials. Calcium Polyp Prev Study Group. Pena, A. S., Wiltshire, E., Gent, R., Hirte, C., and Couper, J. Folic acid improves endothelial function in children and adolescents with type 1 diabetes. Bedford Laboratories. View abstract. View abstract. View abstract. 1981;19(1):57-60. Cancer Epidemiol. Am.J Clin.Nutr 1994;60(6):930-935. Negrao L, Almeida P, Alcino S, et al. View abstract. Do patients with rheumatoid arthritis established on methotrexate and folic acid 5 mg daily need to continue folic acid supplements long term? Gynecol.Obstet.Invest 1981;12(6):294-304. Buysschaert M, Wallemacq PE, Dramais AS, Hermans MP. NVC’s commitment to providing premium-quality products at affordable products and their strict adherence to Good Manufacturing Practice (GMP) guidelines has ensured their status as one of the top manufacturers of supplements. A. and Bhutta, Z. Haan, M. N., Miller, J. W., Aiello, A. E., Whitmer, R. A., Jagust, W. J., Mungas, D. M., Allen, L. H., and Green, R. Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging. View abstract. Alter HJ, Zvaifler NJ, Rath CE. Hendel J, Dam M, Gram L, et al. J Urol. Klipstein FA, Berlinger FG, Reed LJ. You can also buy lower dose tablets from pharmacies and supermarkets. A., Tang, M. X., Shea, S., Miller, J., Green, R., and Mayeux, R. Plasma homocysteine levels and risk of Alzheimer disease. View abstract. View abstract. 2008;135(3):770-80. 2007;79(1):8-15. Tolmunen T, Voutilainen S, Hintikka J, et al. View abstract. Herrmann, W. Significance of hyperhomocysteinemia. 2017;51(3):247-253. Christian, P. Micronutrients, birth weight, and survival. View abstract. Effectiveness of folic acid supplementation in pregnancy on reducing the risk of small-for-gestational age neonates: a population study, systematic review and meta-analysis. Folate deficiency. Please ONLY vote on products you have tried. Ann Intern Med 1994;121:833-41. View abstract. You can get them from pharmacies, large supermarkets, health food stores, or on prescription from a GP. Taking folic acid and taking phenytoin (Dilantin) might decrease the effectiveness of phenytoin (Dilantin) and increase the possibility of seizures. Breast Cancer Res Treat. Eur J Cardiovasc.Prev.Rehabil 2004;11(5):416-420. Omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trial. BMC Med. Pain Manag 2014;4(3):191-6. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.© Therapeutic Research Faculty . Arch.Dis.Child 1971;46(246):189-194. Lekakis, J. P., Papamichael, C. M., Papaioannou, T. G., Dagre, A. G., Stamatelopoulos, K. S., Tryfonopoulos, D., Protogerou, A. D., Stamatelopoulos, S. F., and Mavrikakis, M. Oral folic acid enhances endothelial function in patients with hypercholesterolaemia receiving statins. 2012;23(8):745-754. J Obstet.Gynaecol.Br Commonw. A., Yakoob, M. Y., Lawn, J. E., Rizvi, A., Friberg, I. K., Weissman, E., Buchmann, E., and Goldenberg, R. L. Stillbirths: what difference can we make and at what cost? JAMA 7-6-2005;294(1):47-55. This survey is being conducted by the WebMD marketing sciences department. View abstract. Blood Purif. Contraception 1991;44:277-88. Annu.Rev Nutr 8-21-2010;30:83-104. Proc.Nutr.Soc. View abstract. Wilson, R. D., Davies, G., Desilets, V., Reid, G. J., Summers, A., Wyatt, P., and Young, D. The use of folic acid for the prevention of neural tube defects and other congenital anomalies. View abstract. Lashner BA. A pilot study with simvastatin and folic acid/vitamin B12 in preparation for the Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH). 2008;4(12):672-681. Am J Clin Nutr 2006;84(5):1128-1133. View abstract. View abstract. Eur J Clin Nutr 1991;45(3):139-144. Eur.J.Pediatr. Am J Clin Nutr. Ann Int Med 2001;135:133-7. Folic acid supplementation for stroke prevention in patients with cardiovascular disease. Arch.Gerontol.Geriatr. Fife, J., Raniga, S., Hider, P. N., and Frizelle, F. A. Folic acid supplementation and colorectal cancer risk: a meta-analysis. Clin Lab 2006;52(7-8):367-374. The effect of cholestyramine on intestinal absorption. Poppell, T. D., Keeling, S. D., Collins, J. F., and Hassell, T. M. Effect of folic acid on recurrence of phenytoin-induced gingival overgrowth following gingivectomy. Zhou, K., Zhao, R., Geng, Z., Jiang, L., Cao, Y., Xu, D., Liu, Y., Huang, L., and Zhou, J. Acta Obstet.Gynecol.Scand. 2019 Jul;311(5):361-367. View abstract. Luchsinger, J. View abstract. View abstract. View abstract. Ubbink, J. Food Nutr Bull 2009;30(4 Suppl):S533-S546. Folate administration reduces circulating homocysteine levels in NIDDM patients on long-term metformin treatment. Indian J Pediatr. Relationship of vitamin B12 and folic acid to memory function. View abstract. View abstract. Folic acid: effect on zinc absorption in humans and in the rat. However it will not treat Vitamin B12 deficiency and will not prevent possible damage to the spinal cord. Coull, B. M., Malinow, M. R., Beamer, N., Sexton, G., Nordt, F., and de, Garmo P. Elevated plasma homocyst(e)ine concentration as a possible independent risk factor for stroke. Roswall, N., Olsen, A., Christensen, J., Dragsted, L. O., Overvad, K., and Tjonneland, A. Micronutrient intake and breast cancer characteristics among postmenopausal women. Chuang, V. T. and Suno, M. Levoleucovorin as replacement for leucovorin in cancer treatment. J Am Diet Assoc 1998;98:49-55. Solimando, R., Bazzoli, F., and Ricciardiello, L. Chemoprevention of colorectal cancer: a role for ursodeoxycholic acid, folate and hormone replacement treatment? The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. Am J Clin Nutr 1988;47(3):413-419. Stamp LK, O'Donnell JL, Frampton C, et al. View abstract. Infants born weighing less than 2500 grams (5 pounds, 8 ounces). Gastroenterology 1970;58:1001. J Affect Disord. View abstract. Wehby GL, Félix TM, Goco N, Richieri-Costa A, Chakraborty H, Souza J, Pereira R, Padovani C, Moretti-Ferreira D, Murray JC. den, Heijer M., Willems, H. P., Blom, H. J., Gerrits, W. B., Cattaneo, M., Eichinger, S., Rosendaal, F. R., and Bos, G. M. Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: A randomized, placebo-controlled, double-blind trial. 1985;92 Suppl 5:1-119. Are There Any Side Effects of Folic Acid? Circulation 2002;(106):741S. In particular, red blood cell formation is dependent upon adequate levels of this vitamin. Figueiredo JC, Grau MV, Haile RW, et al. 7th ed. Folic Acid (AHFS Monograph)... +3 more; Related treatment guides. Kabat, G. C., Miller, A. Freudenheim JL, Graham S, Marshall JR, et al. Pathansali, R., Mangoni, A. Doctoral dissertation. Woodside JV, Yarnell JW, McMaster D, et al. Folic acid and risk of prostate cancer: Results from a randomized clinical trial. Aghamohammadi, V., Gargari, B. P., and Aliasgharzadeh, A. Oakley, G. P., Jr. Folic acid-preventable spina bifida: a good start but much to be done. High levels of homocysteine have been linked to heart disease and stroke. Batu, A. T., Toe, T., Pe, H., and Nyunt, K. K. A prophylactic trial of iron and folic acid supplements in pregnant Burmese women. Hadler, M. C., Sigulem, D. M., Alves, Mde F., and Torres, V. M. Treatment and prevention of anemia with ferrous sulfate plus folic acid in children attending daycare centers in Goiania, Goias State, Brazil: a randomized controlled trial. The Centers for Disease Control and Prevention recommends that all women who are of reproductive age take 400 micrograms of folic acid every day, and certain foods are fortified with folic acid. Effects of folic acid treatment on homocysteine levels and vascular disease in hemodialysis patients. Secondary prevention with folic acid: effects on clinical outcomes. Gandy, G. and Jacobson, W. Influence of folic acid on birthweight and growth of the erythroblastotic infant. View abstract. N Engl.J Med 12-24-1992;327(26):1832-1835. View abstract. 2012;122(3):624-35. Cancer Lett. De, Wals P., Tairou, F., Van Allen, M. I., Uh, S. H., Lowry, R. B., Sibbald, B., Evans, J. Ramakrishnan, U., Grant, F., Goldenberg, T., Zongrone, A., and Martorell, R. Effect of women's nutrition before and during early pregnancy on maternal and infant outcomes: a systematic review. Acta Psychiatr.Scand. View abstract. View abstract. Liem, A. H., van Boven, A. J., Veeger, N. J., Withagen, A. J., Robles de Medina, R. M., Tijssen, J. G., and van Veldhuisen, D. J. Efficacy of folic acid when added to statin therapy in patients with hypercholesterolemia following acute myocardial infarction: a randomised pilot trial. Vitamin B12 and folic acid serum levels in diabetics under various therapeutic regimens. A. Folic acid improves endothelial dysfunction in type 2 diabetes--an effect independent of homocysteine-lowering. Guidelines for monitoring drug therapy in rheumatoid arthritis. View abstract. Qin, X., Xu, M., Zhang, Y., Li, J., Xu, X., Wang, X., Xu, X., and Huo, Y. Lancet 1992;339:1003-7. Paspatis, G. A. and Karamanolis, D. G. Folate supplementation and adenomatous colonic polyps. Red blood cell folate is associated with the development of dysplasia and cancer in ulcerative colitis. Sanjoaquin, M. A., Allen, N., Couto, E., Roddam, A. W., and Key, T. J. Folate intake and colorectal cancer risk: a meta-analytical approach. 2010;140(9):1661-1668. This affordable folic acid product is perfect for prenatal supplementation and for anyone with a folate deficiency. Dietary and other methyl-group availability factors and pancreatic cancer risk in a cohort of male smokers. 2008;8:24. Birth defects. Almeida, O. P., McCaul, K., Hankey, G. J., Norman, P., Jamrozik, K., and Flicker, L. Homocysteine and depression in later life. Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during longterm, low dose methotrexate therapy for rheumatoid arthritis: implications for cardiovascular disease prevention. Christiansen, C., Rodbro, P., and Nielsen, C. T. Iatrogenic osteomalacia in epileptic children. 2011;94(1):33-38. View abstract. Transplantation 5-15-2003;75(9):1551-1555. Effect of routine iron supplementation with or without folic acid on anemia during pregnancy. View abstract. Established in 1982, Source Naturals quickly became a pioneer of the dietary supplement industry. 1984;142(2):78-82. Am J Dig Dis 1972;17:731-4. Br Med J 2004;329:1376. Mahomed, K., James, D. K., Golding, J., and McCabe, R. Zinc supplementation during pregnancy: a double blind randomised controlled trial. View abstract. [Ulcerative colitis. 7-8-2002;181(1):65-71. JAMA 1995;274:1049-57. View abstract. You also have the option to opt-out of these cookies. Sandler, R. S., Halabi, S., Baron, J. View abstract. Cancer Epidemiol.Biomarkers Prev. Function of the normal human microflora. Sundown Naturals is committed to providing products that are as natural as possible. Yang, H. T., Lee, M., Hong, K. S., Ovbiagele, B., and Saver, J. L. Efficacy of folic acid supplementation in cardiovascular disease prevention: an updated meta-analysis of randomized controlled trials. Eur.J.Cancer 2004;40(8):1250-1254. Diabetes. Folic acid is the man-made form of folate. J Neurol 1993;240:305-8. View abstract. View abstract. Cochrane Database Syst Rev 2003;(2):CD003390.. View abstract. An 8-year study of people in their 70's found that cognitive functioning (memory … A disorder that causes leg discomfort and an irresistible urge to move the legs (restless legs syndrome or RLS). 2011;25(4-5):555-568. Figueiredo, J. C., Levine, A. J., Grau, M. V., Barry, E. L., Ueland, P. M., Ahnen, D. J., Byers, T., Bresalier, R. S., Summers, R. W., Bond, J., McKeown-Eyssen, G. E., Sandler, R. S., Haile, R. W., and Baron, J. View abstract. 2012;12:CD004736. View abstract. View abstract. Folic acid therapy in the fragile X syndrome. A., Smith, G. D., Talmud, P. J., van, Duijn C., Humphries, S. E., Price, J. F., Ebrahim, S., Lawlor, D. A., Hankey, G. J., Meschia, J. F., Sandhu, M. S., Hingorani, A. D., and Casas, J. P. Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. Your body also needs folic acid to make normal red blood cells and prevent a type of anemia (folate-deficiency anemia). Swart KM, Ham AC, van Wijngaarden JP, et al. 2002;39(6):851-857. View abstract. 2007;86(2):434-443. 1975;46(4):347-350. View abstract. Applies to folic acid: compounding powder, injectable solution, oral tablet Felkner, M., Suarez, L., Hendricks, K., and Larsen, R. Implementation and outcomes of recommended folic acid supplementation in Mexican-American women with prior neural tube defect-affected pregnancies. No effect of vitamin B-12 treatment on cognitive function and depression: a randomized placebo controlled study. B. View abstract. View abstract. J Clin Gastroenterol 2008;42 Suppl 3 Pt 2:S179-S184. Dement.Geriatr Cogn Disord 2002;13(4):225-234. View abstract. Nutr.Clin Pract. This type of deficiency is no longer a problem in many countries that fortify foods such as cereal and pasta with folic acid. View abstract. Some research shows that taking folic acid doesn't reduce the risk of death in people with heart disease. J Affect Disord 1989;16:103-7.. View abstract. View abstract. Arch Dis.Child 2009;94(3):180-184. Kuo, H. K., Sorond, F. A., Chen, J. H., Hashmi, A., Milberg, W. P., and Lipsitz, L. A. Cutis 1992;50:39-42. A., Terry, M. B., Neugut, A. I., and Santella, R. M. One-carbon metabolism, MTHFR polymorphisms, and risk of breast cancer. Am J Prev.Med 2010;38(5):569-570. Voutilainen S, Rissanen TH, Virtanen J, et al. Folic acid (also known as folate) is a B-vitamin found in many foods, including dark green leafy vegetables, fruits, nuts, beans, peas, dairy products, meat, eggs, and grains. 2012;32(7):701-2. Multicentric study of efficacy of periconceptional folic acid containing vitamin supplementation in prevention of open neural tube defects from India. Krogh-Jensen M, Ekelund S, Svendsen L. Folate and homocysteine status and haemolysis in patients treated with sulphasalazine for arthritis. Research shows that taking folic acid with other vitamins including vitamin B6 and vitamin B12 does not prevent cataracts. 2014;167:306-11. View abstract. 95 (£269.79/kg) Save more with Subscribe & Save. View abstract. Enhancement of recovery from psychiatric illness by methylfolate. View abstract. View abstract. Ortega RM, Manas LR, Andres P, et al. Malouf, R. and Grimley, Evans J. Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people. Rom.J Gastroenterol 2003;12(4):283-286. Presented at a meeting of the American Heart Association, late breaking trials; New Orleans. This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Roberts, P. M., Arrowsmith, D. E., Lloyd, A. V., and Monk-Jones, M. E. Effect of folic acid treatment on premature infants. Botez MI, Cadotte M, Beaulieu R, et al. Mattson, R. H., Gallagher, B. Moodley J and Norman RJ. View abstract. Vos E. Multivitamin supplements are effective and inexpensive agents to lower homocysteine levels. J Alzheimers.Dis. View abstract. New Engl J Med 1981;305:1513-7. Woo KS, Chook P, Lolin YI, et al. View abstract. Nutr.Hosp. View abstract. Jenwitheesuk K, Surakunprapha P, Jenwitheesuk K, et al. Arthritis Rheum. View abstract. N Engl J Med 1997;337:69-76. Shafer RB, Nuttall FQ. Ann Trop Med Parasitol. Am J Med Sci. Lin, J., Cook, N. R., Albert, C., Zaharris, E., Gaziano, J. M., Van, Denburgh M., Buring, J. E., and Manson, J. E. Vitamins C and E and beta carotene supplementation and cancer risk: a randomized controlled trial. View abstract. View abstract. 1998;91(4):585-590. View abstract. de Bree A, Verschuren WM, Blom HJ, Kromhout D. Association between B vitamin intake and plasma homocysteine concentration in the general Dutch population aged 20-65 y. Matsubara S, Imai K, Murayama K, Higashizawa T. Severe liver dysfunction during nausea and vomiting of pregnancy: folic acid supplement as a suggested culprit. Am J Med Genet 1992;44:676-82. Curr Opin.Oncol. View abstract. Clarke, R., Lewington, S., and Landray, M. Homocysteine, renal function, and risk of cardiovascular disease. Birth Defects Res A Clin Mol.Teratol. NOW Foods Folic Acid is another top-rated folic supplement. Effects of moderate-dose versus high-dose trimethoprim on serum creatinine and creatinine clearance and adverse reactions. Arch.Dis.Child 1979;54(9):699-702. 2006;22(1):99-107. View abstract. Effects of prenatal multimicronutrient supplementation on pregnancy outcomes: a meta-analysis. 2015;33(9):1897-906. Hvas, A. M., Juul, S., Lauritzen, L., Nexo, E., and Ellegaard, J. Hirsch, S., Pia, De la Maza, Yanez, P., Glasinovic, A., Petermann, M., Barrera, G., Gattas, V., Escobar, E., and Bunout, D. Hyperhomocysteinemia and endothelial function in young subjects: effects of vitamin supplementation. Wilcken, D. E. and Wilcken, B. J Rheumatol 1993;20(6):950-952. Stolzenberg-Solomon, R. Z., Chang, S. C., Leitzmann, M. F., Johnson, K. A., Johnson, C., Buys, S. S., Hoover, R. N., and Ziegler, R. G. Folate intake, alcohol use, and postmenopausal breast cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. A., Kucuk, O., Levi, E., Axelrod, B. N., Patel, B. Folic Acid 5mg - Bulk Pack for 480 Days - only 1/4 Tablet a Day - Vegan - high dose folic Acid - 120 Tablets 4.5 out of 5 stars 170 £12.95 £ 12 . View abstract. Folic acid supplements are essential for maintaining a healthy lifestyle among newborns and pregnant women alike. Cochrane.Database.Syst.Rev. 2003;16(3):156-159. Steinbach G, Lynch PM, Phillips RK, et al. J Natl Cancer Inst 2012;104(20):1562-75. Gastroenterology 1995;108(4):1083-1087. Harrison, K. A. Effect of homocysteine-lowering therapy on vascular endothelial function and exercise performance in coronary patients with hyperhomocysteinaemia. Homocysteine lowering effect of different multivitamin preparations in patients with end-stage renal disease. View abstract. Taking folic acid before getting pregnant or soon after might reduce the risk of having a baby that is too small at birth. View abstract. Decline in the prevalence of neural tube defects following folic acid fortification and its cost-benefit in South Africa. 2012;66(6):544-551. 2010;19(5):360-365. Applying folic acid to the gums seems to prevent gum problems caused by phenytoin. Some limited evidence has found that elderly people who consume more folic acid in the diet or from supplements appear to have a lower risk of developing Alzheimer disease than people who consume less folic acid. View abstract. Zhu S, Mason J, and Shi Y. Eur J Clin Invest 1999;29(8):659-662. Folic acid supplementation for prevention of mood disorders in young people at familial risk: a randomised, double blind, placebo controlled trial. Generally speaking, folic acid causes few if any side effects in most people. Laryngoscope 2012;122(3):624-635. 2011;34(1):83-91. Fleming, A. F., Martin, J. D., Hahnel, R., and Westlake, A. J. Jensen, O. N. and Olesen, O. V. Subnormal serum folate due to anticonvulsive therapy. A., and Uauy, Dagach R. [Effect of folate and related nutrients on cognitive function in older people; systematic review]. Zhu, Y., He, Z. Y., and Liu, H. N. Meta-analysis of the relationship between homocysteine, vitamin B(1)(2), folate, and multiple sclerosis. View abstract. Osifo, B. O. Complement Ther Clin Pract. Folic acid is a synthetic (human-made) form of folate. View abstract. Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention. This is a very effective folic acid supplement, and the addition of vitamin B12 gives it a distinctive advantage. Taking a daily prenatal vitamin — ideally starting three months before conception — can help ensure women get enough of this essential nutrient. B., Reynolds, E. H., and Glass, D. Folate therapy in epilepsy. View abstract. View abstract. Stroke 2002;33:1183-8.. View abstract. J Natl.Cancer Inst. Int J Epidemiol. Ravaglia, G., Forti, P., Maioli, F., Martelli, M., Servadei, L., Brunetti, N., Pantieri, G., and Mariani, E. Conversion of mild cognitive impairment to dementia: predictive role of mild cognitive impairment subtypes and vascular risk factors. View abstract. View abstract. Sharp, L., Little, J., Schofield, A. C., Pavlidou, E., Cotton, S. C., Miedzybrodzka, Z., Baird, J. O., Haites, N. E., Heys, S. D., and Grubb, D. A. Folate and breast cancer: the role of polymorphisms in methylenetetrahydrofolate reductase (MTHFR). Placebo controlled trial Avenell, A. P. Adjuvant treatment of hyperhomocysteinemia to folic acid supplementation inhibits of! Dhole S. calcium supplementation and prevention of cardiovascular events J Intern.Med 2003 ; 23:309-13.. View abstract in! Thompson, P. J., Moore, V. M., Felix, C. Iatrogenic. Su J, et al C. Endpoints for homocysteine-lowering trials ; 14 ( 3 ):731-7 C. and,... V. A., Vermaak, W. L., and artificial additives B12 in vitiligo a... 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